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A vape is sometimes called an e-cigarette, vape pen, e-hookah, or mod. All of these names refer to an electronic tobacco product. Vapes typically have a liquid that is heated to create an aerosol, which the user inhales. Vapes can contain high amounts of nicotine, which is harmful to your brain and can cause addiction.
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Food and Drug Administration (FDA). Vaporizers, E-Cigarettes, and other ENDS. U.S. Food and Drug Administration. https://www.fda.gov/tobacco-products/products-ingredients-components/vaporizers-e-cigarettes-and-other-electronic-nicotine-delivery-systems-ends.
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Hiler M, Breland A, et al. Electronic cigarette user plasma nicotine concentration, puff topography, heart rate, and subjective effects: Influence of liquid nicotine concentration and user experience. Exp Clin Psychopharmacol. 2017; 25(5)380-392.
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A disposable vape is designed to be used and thrown away once the e-liquid has run out. However, like other vapes, disposable vapes can contain nicotine, flavorings, propylene glycol, and glycerin, which are heated into an aerosol that users inhale. Neither is safe to use.
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Vapes can expose your lungs to harmful chemicals, such as formaldehyde and acrolein, and toxic metal particles, such as chromium, nickel, and lead.
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Goniewicz ML, Knysak J, Gawron M, et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tobacco Control. 2014; 23(2):133-139.
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Olmedo P, Goessler W, Tanda S, et al. Metal concentrations in e-cigarette liquid and aerosol samples: the contribution of metallic coils. Environmental Health Perspectives (Online). 2018; 126(2).
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There’s no such thing as a “better” vape. All nicotine products, including cartridge-based and disposable vapes, can expose your brain to nicotine and harm your health. This can disrupt brain development and cause long-term effects on attention, learning, and memory that promote addiction to nicotine.
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U.S. Department of Health and Human Services (USDHHS). E-Cigarette Use Among Youth and Young Adults: A Report of the Surgeon General. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2016.
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England LJ, Aagaard K, Bloch M, et al. Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products. Neuroscience & Biobehavioral Reviews. 2017; 72:176-189.
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Dwyer JB, McQuown SC, Leslie FM. The dynamic effects of nicotine on the developing brain. Pharmacology & Therapeutics. 2009; 122(2):125-39.
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Slotkin TA. Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates. Toxicology and Applied Pharmacology. 2004; 198(2), 132-151.
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Connor DA, Gould TJ. Chronic fluoxetine ameliorates adolescent chronic nicotine exposure-induced long-term adult deficits in trace conditioning. Neuropharmacology. 2017; 125:272-283.
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Holliday ED, Gould TJ. Chronic Nicotine Treatment During Adolescence Attenuates the Effects of Acute Nicotine in Adult Contextual Fear Learning. Nicotine & Tobacco Research. 2017; 19(1):87-93.
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Counotte DS, Spijker S, Van de Burgwal LH, et al. Long-lasting cognitive deficits resulting from adolescent nicotine exposure in rats. Neuropsychopharmacology. 2009; 34(2):299-306.
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Fountain SB, Rowan JD, Kelley BM, Willey AR, Nolley EP. Adolescent exposure to nicotine impairs adult serial pattern learning in rats. Exp Brain Res. 2008; 187(4):651-656.
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Not all vapes contain nicotine, but most do. And regardless of whether they have nicotine, all vapes can contain toxic chemicals. E-liquids, made primarily from propylene glycol and glycerol, break down into harmful chemicals known to cause lung damage and cancer.
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Goniewicz ML, Hajek P, McRobbie H. Nicotine content of electronic cigarettes, its release in vapour and its consistency across batches: regulatory implications. Addiction. 2014; 109(3)500-7.
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Rubinstein M, Delucchi K, Benowitz N, Ramo D. Adolescent exposure to toxic volatile organic chemicals from e-cigarettes. Pediatrics. 2018; 141(4):e20173557.
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Food and Drug Administration (FDA). Understanding the Health Impact and Dangers of Smoke and 'Vapor'. https://www.fda.gov/news-events/fda-voices-perspectives-fda-leadership-and-experts/understanding-health-impact-and-dangers-smoke-and-vapor.
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When you vape, you can inhale toxic metal particles like nickel, chromium, and lead.
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Williams M, Villarreal A, Bozhilov K, Lin S, Talbot P. Metal and silicate particles including nanoparticles are present in electronic cigarette cartomizer fluid and aerosol. PLoS One. 2013; 8(3):e57987.
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Olmedo P, Goessler W, Tanda S, et al. Metal concentrations in e-cigarette liquid and aerosol samples: the contribution of metallic coils. Environmental Health Perspectives (Online). 2018; 126(2).
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Vapes have not been approved to help people quit smoking. The safest option for your health is to be completely tobacco-free, since nicotine in any form can be disruptive to brain development. Quitting vaping is hard, but there are resources that can help: https://teen.smokefree.gov/quit-vaping
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Chun LF, Moazed F, Calfee CS, Matthay MA, Gotts JE. Pulmonary toxicity of e-cigarettes. Am J Physiol Lung Cell Mol Physiol. 2017;313(2):L193–L206. doi:10.1152/ajplung.00071.2017.
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Madison M, Landers C, Gu B, et al. Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine. Journal of Clinical Investigation. 2019; 129(10).
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Schweitzer KS, Chen SX, Law S, et al. Endothelial disruptive proinflammatory effects of nicotine and ecigarette vapor exposures. Am J Physiol Lung Cell Mol Physiol. 2015;309(2):L175–L187. doi:10.1152/ajplung.00411.2014.
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Nicotine is a highly addictive drug that teens are more sensitive to because their brains are still developing. Using nicotine at a young age can make it easier to be addicted and have long-term effects on attention, learning, and memory that promote addiction to nicotine.
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Connor DA, Gould TJ. Chronic fluoxetine ameliorates adolescent chronic nicotine exposure-induced long-term adult deficits in trace conditioning. Neuropharmacology. 2017; 125:272-283.
-
Holliday ED, Gould TJ. Chronic Nicotine Treatment During Adolescence Attenuates the Effects of Acute Nicotine in Adult Contextual Fear Learning. Nicotine & Tobacco Research. 2017; 19(1):87-93.
-
Counotte DS, Spijker S, Van de Burgwal LH, et al. Long-lasting cognitive deficits resulting from adolescent nicotine exposure in rats. Neuropsychopharmacology. 2009; 34(2):299-306.
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Fountain SB, Rowan JD, Kelley BM, Willey AR, Nolley EP. Adolescent exposure to nicotine impairs adult serial pattern learning in rats. Exp Brain Res. 2008; 187(4):651-656.
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Vaping can expose you to cancer-causing chemicals, and metals that are known to be toxic to your lungs, and seriously addictive levels of nicotine. Some users may also experience coughing and wheezing, nausea, vomiting, headache, and dizziness.
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Goniewicz ML, Knysak J, Gawron M, et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tobacco Control. 2014; 23(2):133-139.
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Cheng T. Chemical evaluation of electronic cigarettes. Tobacco Control. 2014; 23:ii11–ii17.
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Bein K, Leikauf GD. Acrolein–a pulmonary hazard. Molecular & Food Research. 2011;55(9):1342-1360.
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Occupational Safety and Health Administration (OSHA). Occupational Safety and Health Standards. Medical surveillance – Formaldehyde. Washington, DC: U.S. Department of Labor, Occupational Safety and Health Administration. https://www.osha.gov/pls/oshaweb/owadisp.show_document?p_table=STANDARDS&p_id=10078. Accessed May 8, 2018.
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Meo SA, Al Asiri SA. Effects of electronic cigarette smoking on human health. Eur Rev Med Pharmacol Sci. 2014;18(21):3315-3319.
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Hua M, Alfi M, Talbot P. Health-related effects reported by electronic cigarette users in online forums. J Med Internet Res. 2013;15(4):e59.
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Motooka Y, Matsui T, Slaton RM, et al. Adverse events of smoking cessation treatments (nicotine replacement therapy and non-nicotine prescription medication) and electronic cigarettes in the Food and Drug Administration Adverse Event Reporting System, 2004-2016. SAGE Open Med. 2018;6:2050312118777953.
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Vape liquids typically consist of propylene glycol, glycerol, nicotine, flavorings, and other chemicals. When heated during use, e-liquids form an inhalable chemical aerosol or “vapor.” Some e-cigarette aerosols can contain cancer-causing chemicals like formaldehyde.
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Goniewicz ML, Knysak J, Gawron M, et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tobacco Control. 2014; 23(2):133-139.
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Cheng T. Chemical evaluation of electronic cigarettes. Tobacco Control. 2014; 23:ii11–ii17.
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Bein K, Leikauf GD. Acrolein–a pulmonary hazard. Molecular & Food Research. 2011;55(9):1342-1360.
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Occupational Safety and Health Administration (OSHA). Occupational Safety and Health Standards. Medical surveillance – Formaldehyde. Washington, DC: U.S. Department of Labor, Occupational Safety and Health Administration. https://www.osha.gov/pls/oshaweb/owadisp.show_document?p_table=STANDARDS&p_id=10078. Accessed May 8, 2018.
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U.S. Department of Health and Human Services (USDHHS). The Health Consequences of Smoking - 50 Years of Progress. A Report of the Surgeon General. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2014.
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Murphy SL, Xu JQ, Kochanek KD. Deaths: Final data for 2010. National Vital Statistics Reports. 2013; 61(4):37-41.
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